胡志棠 醫師

醫師代碼:2306我要掛號

專 長

  • 一般胃腸肝膽科
  • 慢性肝炎
  • 肝硬化
  • 肝癌
  • 分子生物學
  • 分子遺傳學
  • 遺傳病及癌症的分子醫學診斷
  • 經鼻內視鏡
  • 換水法大腸鏡
  • 腹部超音波

現 職

  • 內科部肝膽腸胃研究中心主任
  • 內科部肝膽腸胃科主治醫師
  • 研究部肝病研究中心專題研究室主持人
  • 慈濟大學部定副教授

 
學 歷

  • 台北醫學大學醫學士
  • 英國劍橋大學分子生物學博士

經 歷

  • 台北馬偕醫院內科部住院醫師
  • 台北醫學大學附設醫院腸胃肝膽科研究員、總醫師
  • 慈濟醫院人體試驗計劃審議委員會總幹事、內科部副主任、消化系功能檢查室主任、肝膽腸胃科主任
  • 慈濟大學醫學系講師、助理教授、腸胃肝膽科主任
  • 英國劍橋大學附設醫院(Addenbrooke’s Hospital)分子肝膽暨肝移植中心研究員
  • 德國柏林分子醫學中心(Max Delbruck Center for Molecular Medicine)研究員
  • 美國國家衛生院(National Institutes of Health)肝病研究中心博士後研究員

簡易介紹
專科證書

  • 內科專科醫師證書
  • 消化系內視鏡專科醫師證書
  • 消化系醫學會專科醫師證書
  • 針灸專科醫師證書
 
專科學會
  • 台灣內科醫學會
  • 台灣消化系醫學會
  • 台灣消化系內視鏡醫學會(第八屆、第九屆理事)
  • 台灣肝臟研究學會
  • 中華針灸醫學會
著 作:

【專書】

  • Wen-Sheng Wu, Chi-Tan HuEditors. Signal Transduction in Cancer Metastasis. Cancer metastasis- Biology and Treatment 15. Springer 2010.【DOI: 10.1007/978-90-481-9522-0, ISBN: 978-90-481-9521-3 (eISBN: 978-90-481-9522-0)】
  • Wen-Sheng Wu, Chi-Tan Hu*. Chapter 2: Microenvironment Triggers EMT, Migration and Invasion of Primary Tumor via Multiple Signal Pathways. Cancer metastasis-Biology and Treatment 15: 9-24. Springer 2010 Nov.
  • Chi-Tan Hu, Jia-Ru Wu, Wen-Sheng Wu*. Chapter 7: Signal Cross Talks for Sustained MAPK Activation and Cell Migration Mediated by Reactive Oxygen Species: The Involvement in Tumor Progression. Cancer metastasis-Biology and Treatment 15: 119-136. Springer 2010 Nov.
  • Selena Y. Lin, Surbhi Jain, Wei Song, Chi-Tan Hu, Ying-Hsiu Su. Chapter 7: Strategic Assay Developments for Detection of HBV 1762T/1764A Double Mutation in Urine of Patients with HBV-Associated Hepatocellular Carcinomas. Hepatocellular Carcinoma-Clinical Research: 139-154. InTech 2012 Mar.【DOI: 10.5772/2483, ISBN 978-953-51-0112-3】
  • Chi-Tan Hu, CL Chen, Zhen-Xiong Lin. Ch.6 Miscellaneous Disorders. 9. Small Bowel Tapeworm. Atlas of Small Intestinal Disorders: Integrated Case Presentation. P206-209. Ho-Chi Book Publishing Co. 2014 Jan.【ISBN 978-986-368-001-7】
  • 胡志棠. Part 2認識肝硬化發病原因與預防. 2-3肝硬化的症狀及徵兆. 肝硬化全書-全國護肝專家教你預防、照護、治療36-46. 如何出版社有限公司2014年5月.【ISBN 978-986-136-389-9】

【影片】


  • 大愛電視台「人體的奧秘系列:人體的超級工廠-肝臟」影片科學顧問(國科會補助) (2014年1月11日首播) 

【專利】

  • 魏誠佑、謝昌衛、盧崑山、夏靜吾、龍輝、蕭正忠、胡志棠。用以治療癌症及/或腫瘤之到手香葉汁LEAF JUICE OF PLECTRANTHUS AMBOINICUS FOR TREATING CANCER AND/OR TUMOR。(專利證書號數I399210)
  • 高立人、鍾承璋、胡志棠、陳明賢。基於雲端運算技術之影像處理系統。(發明第I498747號)

【近五年期刊論文】

  •  Chi-Tan Hu*. Cotton pledget packing versus topical spray for nasal preparation: merits and demerits are answered by a strict randomized controlled trial. European Archives of Oto-Rhino-Laryngology270(5):1763-1764. 2013 May. (SCI)
  • Chi-Tan Hu, Chuan-Chu Cheng, Siou-Mei Pan, Jia-Ru Wu, Wen-Sheng Wu*. PKC mediates fluctuant ERK-paxillin signaling for hepatocyte growth factor-induced migration of hepatoma cell HepG2. Cellular Signalling 25(6):1457–1467, 2013 Jun. (SCI)
  • Chi-Tan Hu, Jia-Ru Wu, Wen-Sheng Wu*. The role of endosomal signaling triggered by metastatic growth factors in tumor progression. Cellular Signalling 25(7):1539-1545.2013 Jul.(SCI)
  • Wen-Lin Lo, Jen-Shung Lin, Wei-Yi Lei, Hao-Chun Yu, Li-Keng Chao, Jui-Sheng Hung, Daw-Chian Tang, Chi-Tan Hu*. Transnasal Endoscopy: Savior for Patients with Endoscopy Phobia. Journal of Internal Medicine of Taiwan 24(4):271-277. 2013 Aug.
  • Chi-Tan Hu*. Let your patients watch and talk during examination: A review of unsedated transnasal endoscopy. Tzu Chi Medical Journal 25(3):139-145. 2013 Sep.
  • Ming-Cheh Chen, Chih-Hsun Yi, Li-Yu Wang, Hans Hsienhong Lin, Chi-Tan Hu*. Difference in the Prevalence of CYP2C19 Poor Metabolizers Among Racial and Ethnic Groups of Eastern Taiwan. Gastroenterological Journal of Taiwan 30(4):300-308. 2013 Dec.
  • Jen-Shung Lin, Wen-Lin Lo, Wei-Yi Lei, Hao-Chun Yu, Li-Keng Chao, Rui-Sheng Hong, Dau-Chen Tang, Chi-Tan Hu*. Historic Progress and New Trend of Nasoenteric Tube Placement. Journal of Internal Medicine of Taiwan24(6):461-468. 2013 Dec.
  • Rong-Nan Chien, Cheng-Yuan Peng, Jia-Horng Kao, Tsung-Hui Hu, Chun-Che Lin, Chi-Tan Hu, Chi-Yi Chen, Tsai-Yuan Hsieh, Han-Chieh Lin, Wan-Long Chuang, on behalf of the Taiwan NA-Registry Group. Higher adherence with 3-year entecavir treatment than lamivudine or telbivudine in treatment-naïve Taiwanese patients with chronic hepatitis B. Journal of Gastroenterology and Hepatology29(1):185-192. 2014 Jan.(SCI)
  • Ming-Cheh Chen, Wei-Yi Lei, Jen-Shung Lin, Chih-Hsun Yi, Deng-ChyangWu, Chi-Tan Hu*. Levofloxacin-Amoxicillin/Clavulanate-Rabeprazole versus a Standard Seven-Day Triple Therapy for Eradication of Helicobacter pylori Infection. BioMed Research International (Journal of Biomedicine and Biotechnology)2014(ID 158520):1-7. 2014 Jun. (SCI)
  • Surbhi Jain, Lijia Xie, Batbold Boldbaatar, Selena Y. Lin, James P. Hamilton, Stephen J. Meltzer, Shun-Hua Chen, Chi-Tan Hu, Timothy M. Block, Wei Song*, Ying-Hsiu Su*. Differential methylation of the promoter and first exon of the RASSF1A gene in hepatocarcinogenesis. Hepatology Research1-14. 2014 Nov. (SCI)
  • Jia-Ru Wu, Chi-Tan Hu, Ren-In You, Pei-Ling Ma, Siou-Mei Pan, Ming-Che Lee, Wen-Sheng Wu*. Preclinical Trials for Prevention of Tumor Progression of Hepatocellular Carcinoma by LZ-8 Targeting c-Met Dependent and Independent Pathways. PLoS One 10(1):e0114495, 1-19. 2015 Jan. (SCI)
  • Chao-Chuan Wu, Chi-Tan Hu%, Ming-Che Lee, Yao-Jen Chang, Siou-Mei Pan, Jia-Ru Wu, Shu-Chuan Lin, Wen-Sheng Wu*. Prevention of Hepatocellular carcinoma progression by the Chinese herb derived peptide Lingzhi-8. Journal of Nature and Science 1(3):e50, 1-3. 2015 Mar.
  • Guang-Hong Jheng, I-Chen Wu, Hsiang-Yao Shih, Meng-Chieh Wu, Fu-Chen Kuo, Huang-Ming Hu, Chung-Jung Liu, Wen-Hung Hsu, Chi-Tan Hu, Ming-Jong Bair, Chao-Hung Kuo, Deng-ChyangWu, Ping-I Hsu*. Comparison of Second-Line Quadruple Therapies with or without Bismuth for Helicobacter pylori Infection. BioMed Research International (Journal of Biomedicine and Biotechnology)2015(ID 163960):1-6. 2015 May. (SCI)
  • Surbhi Jain, Ting-Tsung Chang, Sitong Chen, Batbold Boldbaatar, Adam Clemens, Selena Y. Lin, Ran Yan, Chi-Tan Hu, Haitao Guo, Timothy M. Block, Wei Song, Ying-Hsiu Su*. Comprehensive DNA methylation analysis of hepatitis B virus genome in infected liver tissues. Scientific Reports5(10478):1-11. 2015 May (SCI)
  • Chi-Tan Hu, Chuan-Chu Cheng, Jia-RuWu, Siou-Mei Pan, Wen-Sheng Wu*. PKCε-mediated c-Met endosomal processing directs fluctuant c-Met-JNK-paxillin signaling for tumor progression of HepG2. Cellular Signalling 27(7):1544-1555. 2015 Jul. (SCI)
  • Jia-Ru Wu, Chi-Tan Hu, Ren-In You, Siou-Mei Pan, Chuan-Chu Cheng, Ming-Che Lee, Chao-Chuan Wu, Yao-Jen Chang, Shu-Chuan Lin, Chang-Shan Chen, Teng-Yi Lin, Wen-Sheng Wu*. Hydrogen peroxide inducible clone-5 mediates reactive oxygen species signaling for hepatocellular carcinoma progression. Oncotarget 6(32):32526-32544. 2015 Oct. (SCI)Chi-Tan Hu*. Anterior meatuscopy is more reliable than a sniff test for predicting nasal patency before transnasal endoscopy. Endoscopy International Open3(6):E538-E546. 2015 Dec.
  • Chung-Yi Lin, Chi-Tan Hu, Chuan-Chu Cheng, Ming-Che Lee, Siou-Mei Pan, Teng-Yi Lin, Wen-Sheng Wu*. Oxidation of heat shock protein 60 and protein disulfide isomerase activates ERK and migration of human hepatocellular carcinoma HepG2. Oncotarget7(10):11067-11082. 2016 Mar. (SCI)
  • Tung-Hung Su, Tsung-Hui Hu, Chi-Yi Chen, Yi-Hsiang Huang, Wan-Long Chuang, Chun-Che Lin, Chia-Chi Wang, Wei-Wen Su, Ming-Yao Chen, Cheng-Yuan Peng, Rong-Nan Chien, Yi-Wen Huang, Horng-Yuan Wang, Chih-Lin Lin, Sheng-Shun Yang, Tsung-Ming Chen, Lein-Ray Mo, Shih-Jer Hsu, Kuo-Chih Tseng, Tsai-Yuan Hsieh, Fat-Moon Suk, Chi-Tan Hu, Ming-Jong Bair, Cheng-Chao Liang, Yung-Chao Lei, Tai-Chung Tseng, Chi-Ling Chen, Jia-Horng Kao*, on behalf of the C-TEAM study group and the Taiwan Liver Diseases Consortium. Four-year entecavir therapy reduces hepatocellular carcinoma, cirrhotic events and mortality in chronic hepatitis B patients. Liver International36(12):1755-1764. 2016 Dec. (SCI)
  • Shi-Ming Lin*, Sheng-Nan Lu, Ping-Tsung Chen, Long-Bin Jeng, Shinn-Cherng Chen, Chi-Tan Hu, Sien-Sing Yang, Marie-Aude Le Berre, Xuan Liu, David Y. Mitchell, Klaas Prins, Joachim Grevel, Carol A. E. Peña, Gerold Meinhardt. HATT: a phase IV, single-arm, open-label study of sorafenib in Taiwanese patients with advanced hepatocellular carcinoma. Hepatology International11(2):199-208. 2017 Mar. (SCI)
  • Chi-Tan Hu, Jia-RuWu, Chuan-Chu Cheng, Wen-Sheng Wu*. The Therapeutic Targeting of HGF/c-Met Signaling in Hepatocellular Carcinoma: Alternative Approaches. Cancers9(6):58, 1-9, 2017 May.(SCI)
  • Yu-Hsi Hsieh*, Chih-Wei Tseng, Chi-Tan Hu, Malcolm Koo, Felix W. Leung. Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation. Gastrointestinal Endoscopy86(1):192-201. 2017 Jul. (SCI)
  • Chi-Tan Hu*, Wei-Yi Lei, Jen-Shung Lin, Jui-Sheng Hung. Endoscopic meatus scoring scale versus sniff test to predict insertability before transnasal endoscopy: A prospective, randomized study. Journal of Gastroenterology and Hepatology32(12):1914-1921. 2017 Dec. (SCI)
  • Wen-Sheng Wu, Ren-In You, Chuan-Chu Cheng, Ming-Che Lee, Teng-Yi Lin, Chi-Tan Hu*. Snail collaborates with EGR-1 and SP-1 to directly activate transcription of MMP 9 and ZEB1. Scientific Reports7(1):17753. 2017 Dec. (SCI)
  • Jeremy Wang, Surbhi Jain, Dion Chen, Wei Song, Chi-Tan Hu*, Ying-Hsiu Su*. Development and Evaluation of Novel Statistical Methods in Urine Biomarker-Based Hepatocellular Carcinoma Screening. Scientific Reports 8(1):3799. 2018 Feb. (SCI)
  • Surbhi Jain, Ying-Hsiu Su, Yih-Ping Su, Sierra McCloud, Ruixia Xue, Tai-Jung Lee, Shu-Chuan Lin, Selena Y. Lin, Wei Song, Jamin D. Steffen, Chi-Tan Hu*. Characterization of the hepatitis B virus DNA detected in urine of chronic hepatitis B patients. BMC Gastroenterology 18(1):40,1-9. 2018 Mar.(SCI)
  • Felix W. Leung, Malcolm Koo, Sergio Cadoni, Premysl Falt, Yu-Hsi Hsieh, Arnaldo Amato, Matteo Erriu, Petr Fojtik, Paolo Gallittu, Chi-Tan Hu, Joseph W. Leung, Mauro Liggi, Silvia Paggi, Franco Radaelli, Emanuele Rondonotti, Vit Smajstrla, Chih-Wei Tseng, Ondrej Urban. Water Exchange Produces Significantly Higher Adenoma Detection Rate Than Water Immersion Pooled Data From 2 Multisite Randomized Controlled Trials. Journal of Clinical Gastroenterology2018/3/2. (SCI)
  • Hui Jia, Malcolm Koo, Yu-Hsi Hsieh, Chih-Wei Tseng, Chi-Tan Hu, Linhui Zhang, MD, Tao Dong, Yanglin Pan, Felix W. Leung*. Factors Associated With Adenoma Detection in Propofol-sedated Patients.Journal of Clinical Gastroenterology2018/6/15. (SCI)
  • Ren-In You, Wen-Sheng Wu, Chuan-Chu Cheng, Jia-Ru Wu, Siou-Mei Pan, Chi-Wen Chen, Chi-Tan Hu*. Involvement of N-glycan in multiple receptor tyrosine kinases targeted by Ling-Zhi-8 for suppressing HCC413 tumor progression. Cancers Accepted 2018/12/18. (SCI)

            

【榮譽】

  • 87年度同時獲得英國劍橋大學分子生物學及倫敦大學King's College肝病研究中心(Institute of Liver Studies)博士班錄取。
  • 93年度慈濟醫學雜誌(第十六卷)優秀論文選拔,基礎醫學組第一名。
  • 94年度慈濟醫學雜誌(第十七卷)優秀論文選拔,基礎醫學組第一名。
  • 98年度Young Investigator Award(YIA) Section亞太特殊研究獎(Asia Pacific Digestive Week, 27–30 Sep 2009, Taipei International Convention, Center Taipei, Taiwan, New Frontier in Digestive Medicine)
  • 99年度第十三屆周大觀文教基金會全球熱愛生命獎章。
  • 99年度慈濟醫院研究績效卓越獎資深人員第三名。
  • 100年度第一、二期慈濟醫院微笑天使選拔第一名。
  • 102年度花蓮慈濟醫院優秀研究論文評選-資深醫師組第三名。
  • 103年度慈濟大學醫學系102學年度教學優良教師。
  • 105年度花蓮慈濟醫院優秀研究論文評選-資深醫師組第三名。
 

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