Practical Application of the COuGH RefluX Score for Patients with Laryngopharyngeal Symptoms: Real-World Assessment in Predicting GERD and PPI Response. Wong MW, Hsiao SH, Wang JH, Hung JS, Liu TT, Lei WY, Yi CH, Chen PR, Gyawali CP, Chen CL.Am J Gastroenterol. 2024 Nov 26. doi: 10.14309/ajg.0000000000003240. Epub ahead of print.
Impact of Esophageal Motility on Microbiome Alterations in Symptomatic Gastroesophageal Reflux Disease Patients With Negative Endoscopy: Exploring the Role of Ineffective Esophageal Motility and Contraction Reserve. Wong MW, Lo IH, Wu WK, Liu PY, Yang YT, Chen CY, Wu MS, Wong SH, Lei WY, Yi CH, Liu TT, Hung JS, Liang SW, Gyawali CP, Chen CL.Neurogastroenterol Motil. 2024 Jul 30;30(3):332-342.
Mucosal integrity and acid sensitivity predict proton pump inhibitor response in patients with heartburn and normal acid exposure. Wong MW, Yi CH, Liu TT, Lei WY, Hung JS, Wang JH, Gyawali CP, Chen CL. Dig Liver Dis. 2025 Apr;57(4):842-848.
Esophageal hypervigilance and visceral anxiety contribute to symptom severity of laryngopharyngeal reflux. Wong MW, Hsiao SH, Wang JH, Yi CH, Liu TT, Lei WY, Hung JS, Liang SW, Lin L, Gyawali CP, Chen PR and Chen CL. American Journal of Gastroenterology. 2023 May 1;118(5):786-793.
Artificial intelligence facilitates measuring reflux episodes and post reflux swallow-induced peristaltic wave index from impedance-pH studies in patients with reflux disease. Wong MW, Liu MX, Lei WY, Liu TT, Yi CH, Hung JS, Liang SW, Lin L, Tseng CW, Wang JH, Wu PA, Chen CL.Neurogastroenterol Motil. 2023 Mar;35(3):e14506.
Esophageal secondary peristalsis following acid infusion and chemical clearance correlate with mucosal integrity and acid sensitivity in GERD patients. Wong MW, Hung JS, Lei WY, Liu TT, Yi CH, Liang SW, Gyawali CP, Wang JH, Chen CL. Therap Adv Gastroenterol. 2023 Jun 29;16:17562848231179329.
Oesophageal hypervigilance and visceral anxiety relate to reflux symptom severity and psychological distress but not to acid reflux parameters.Wong MW, Liu TT, Yi CH, Lei WY, Hung JS, Cock C, Omari T, Gyawali CP, Liang SW, Lin L, Chen CL. Aliment Pharmacol Ther. 2021 Oct;54(7):923-930
Analysis of contractile segment impedance during straight leg raise maneuver using high-resolution impedance manometry increases diagnostic yield in reflux disease. Wong MW, Liu TT, Yi CH, Lei WY, Hung JS, Omari T, Cock C, Liang SW, Gyawali CP, Chen CL. Neurogastroenterology & Motility. 2021;00:e14135.
Effect of prucalopride on sildenafil-induced inhibition of esophageal peristalsis in healthy adults. Wong MW, Liu TT, Yi CH, Hung JS, Lei WY, Liang SW, Orr WC, Chen CL. J Gastroenterol Hepatol. 2021 Jun;36(6):1556-1561.
Esophageal acid burden in reflux patients with normal endoscopy: Does esophageal peristalsis matter? Wong MW, Hung JS, Liu TT, Yi CH, Lei WY, Liang SW, Orr WC, Chen CL. J Formos Med Assoc. 2021 Jun 2;S0929-6646(21)00236-9.
Effects of phosphodiesterase-5 inhibitor sildenafil on esophageal secondary peristalsis: studies with high-resolution manometry. Wong MW, Yi CH, Liu TT, Lei WY, Hung JS, Liu CZ, Chen CL. J Gastroenterol Hepatol. 2021 Feb;36(2):430-435.
Influence of sildenafil on esophageal motor function in humans: studies using high-resolution manometry. Wong MW, Hung JS, Lei WY, Liu TT, Yi CH, Chen CL. Neurogastroenterol Motil. 2020 Apr 23;e13840.
Esophageal acid sensitivity in patients with gastroesophageal reflux disease: does esophageal hypomotility matter? Wong MW, Hung JS, Lei WY, Liu TT, Yi CH, Chen CL. Neurogastroenterol Motil. 2019 Nov;31(11):e13700.
Clinical and psychological characteristics in gastroesophageal reflux disease patients overlapping with laryngopharyngeal reflux symptoms. Wong MW, Bair MJ, Chang WC, Hsu CS, Hung JS, Liu TT, Yi CH, Lei WY, Vaezi MF, Gyawali CP, Chen CL.J Gastroenterol Hepatol. 2019 Oct;34(10):1720-1726.
Gamma‐aminobutyric acid receptor type B agonist baclofen inhibits acid‐induced excitation of secondary peristalsis but not heartburn sensation. Wong MW, Hung JS, Liu TT, Yi CH, Lei WY, Chen CL. J Gastroenterol Hepatol. 2019 Feb;34(2):370-375.
Assessment of esophageal function using provocative tests during high resolution manometry: a single-center experience. Wong MW, Lei WY, Hung JS, Liu TT, Yi CH, Chen CL. J Formos Med Assoc. 2019 Jan;118(1 Pt 2):244-248.
Validated Clinical Score to Predict Gastroesophageal Reflux in Patients With Chronic Laryngeal Symptoms: COuGH RefluX. Amanda J Krause, Alexander M Kaizer, Dustin A Carlson, Walter W Chan, Chien-Lin Chen, C Prakash Gyawali, Andrew Jenkins, John E Pandolfino, Vinathi Polamraju, Ming-Wun Wong, Madeline Greytak, Rena Yadlapati. Clin Gastroenterol Hepatol. 2024 Jun;22(6):1200-1209.e1.
Diagnostic Yield of Ambulatory Reflux Monitoring Systems for Evaluation of Chronic Laryngeal Symptoms. Amanda J Krause, Madeline Greytak, Alexander M Kaizer, Dustin A Carlson, Walter W Chan, Chien-Lin Chen, C Prakash Gyawali, Andrew Jenkins, John E Pandolfino, Vinathi Polamraju, Ming-Wun Wong, Rena Yadlapati. Am J Gastroenterol. 2024 Apr 1;119(4):627-634.
The Lyon Score: A Novel Reflux Scoring System Based on the Lyon Consensus 2.0 That Associates With Treatment Outcome From Antireflux Therapy. Gyawali CP, Marchetti L, Rogers BD, Chan WW, Wong MW, Visaggi P, Rengarajan A, Carlson DA, Savarino E, de Bortoli N, Chen CL, Pandolfino JE.Am J Gastroenterol. 2025 May 1;120(5):1009-1018.
Validation of Esophageal Global Symptom Severity as a Patient-Reported Outcome for Evaluation of Reflux Symptoms. Chan WW, Schroeder M, Richardson A, Shah N, Muftah M, Muftah S, Siboni S, Sozzi M, Wong MW, Chen CL, Gyawali CP; Milan Score Working Group.Am J Gastroenterol. 2025 Apr 23. doi: 10.14309/ajg.0000000000003499. Epub ahead of print.
