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陳灝平研究員

現職： 慈濟大學醫學系生化學科教授
E-mail： hpchen@mail.tcu.edu.tw
分機： (03) 8565301 ext. 2433 (office)/ 2434 (lab)

學歷：
英國劍橋大學生化系博士 (1998)
台灣大學生化科學所碩士 (1992)
台灣大學植物系學士 (1989)

經歷

1.慈濟大學醫學系生化學科教授 (2021/02~ now)
2.花蓮慈濟醫院中西醫合療研究發展中心 研究員 (2022/7 ~ now)
3.慈濟大學醫學系生化學科副教授 (2011/08 ~ 2021/01)
4.花蓮慈濟醫院中西醫合療研究發展中心 副研究員 (2018/9 ~ 2022/6)
5.加拿大英屬哥倫比亞大學微生物與免疫學系研究技師 (2008/2-2011/7)
6.國立台北科技大學化工系副教授 (2003/8-2008/2)
7.淡江大學化學系 副教授 (2002/8-2003/7)
8.中國醫藥大學醫學系生化科 副教授 (1998/12-2002/7)
9.中央研究院生物化學所 訪問學者 (1999/7-1999/9)

五年內SCI論文成果(*表通訊作者)

1. Ho TJ, Lin JH, Lin SZ, Tsai WT, Wu JR*, Chen HP.* Isolation, identification, and characterization of bioactive peptides in human bone cells from tortoiseshell and deer antler gelatin. (2023) International Journal of Molecular Sciences 24(2), 1759.
2. Wu JR, Lu PC, Khine AA, Simaremare SR, Hung CC, Yiin LM, Ho TJ, Tung CH,* Chen HP.* Borneol dehydrogenase from Pseudomonas sp. TCU-HL1 possesses novel quinuclidinone reductase activities. (2023) Biocatalysis and Biotransformation 41(1), 38-45.
3. Ho TJ, Tsai PH, Hsieh CH, Lin JH, Lin YW, Wu JR,* Chen HP.* Role of herbal extracts of catechu from Uncaria gambir in the treatment of chronic diabetic wounds. (2023) Pharmaceuticals 16(1), 66.
4. Lai SC, You RI, Chen TT, Chang Y, Liu CZ, Chen HP,* Wu C.* Rapid identification of commercial frankincense products by MALDI-TOF mass spectrometry. (2022) Combinatorial Chemistry & High Throughput Screening 25(5), 895-905.
5. Wu JR, Lu YC, Hung SJ, Lin JH, Chang KC, Chen JK, Tasi WT, Ho TJ,* Chen HP.* Antimicrobial and immunomodulatory activity of herb extracts used in burn wound healing: “San Huang Powder”. (2021) Evidence-Based Complementary and Alternative Medicine, Volume 2021, Article ID 2900060.
6. Lu CC, Yang CC, Chiu YJ, Tsai FJ, Hsu YM, Yin MC, Juan YN, Ho TJ,* Chen HP.* Dracorhodin perchlorate enhances wound healing via β-catenin, ERK/p38 and AKT signaling in human HaCaT keratinocytes. (2021) Experimental and Therapeutic Medicine 22(2), 822.
7. Hung SJ, Hong YA, Lin KY, Hua YW, Kuo CJ, Hu A,*, Shih TL,* Chen HP.* Efficient photodynamic killing of gram-positive bacteria by synthetic curcuminoids. (2020) International Journal of Molecular Sciences 21(23), 9024.
8. Khine AA, Lu PC, Ko TP, Huang KF, Chen HP.* Cloning, expression, identification and characterization of borneol dehydrogenase isozymes in Pseudomonas sp. TCU-HL1. (2020) Protein Expression and Purification 175, 105715.
9. Tung CH, Lu YT, Kao WT, Liu JW, Lai YH, Jiang SJ, Chen HP,* Shih TL.* Discovery of a more potent anti-cancer agent than C4-benzazole 1,8-naphthalimide derivatives against murine melanoma. (2020) Journal of the Chinese Chemical Society 67(7), 1254-1262.
10. Khine AA, Yang MY, Hu A, Lin GH, Toh YH, Chen HP.* Production of optically pure (-)-borneol by Pseudomonas monteilii TCU-CK1 and characterization of borneol dehydrogenase involved. (2020) Enzyme and Microbial Technology 139, 109586.
11. Ho TJ, Chen JK, Li TS, Lin JH, Hsu YH, Wu JR, Tsai WT, Chen HP.* The curative effects of the traditional Chinese herbal medicine “Jinchuang ointment” on excisional wounds. (2020) Chinese Medicine 15, 41.
12. Hsu WH, Tsai WT, Hung SJ, Cheng HC, Hsu CH, Ho TJ,* Chen HP.* Treatment of leprosy wounds with “Jinchuang Ointment”, a traditional Chinese herbal medicine complex. (2019) Leprosy Review 90(4), 460-468.
13. Wu C, Cai XQ, Chang Y, Chen CH, Ho TJ, Lai SC, Chen HP.* Rapid identification of dragon blood samples from Daemonorops draco, Dracaena cinnabari and Dracaena cochinchinensis by MALDI-TOF mass spectrometry​. (2019) Phytochemical Analysis 30(6), 720-726.
14. Krishnaraj P, Chang Y, Ho TJ, Lu NC, Lin MD,* Chen HP.* In vivo pro-angiogenic effects of dracorhodin perchlorate in zebrafish embryos: a novel bioactivity evaluation platform for commercial dragon blood samples. (2019) Journal of Food and Drug Analysis 27(1), 259-265.
15. Yang MY, Khine AA, Liu JW, Cheng HC, Hu A,* Chen HP,* Shih TL.* Resolution of isoborneol and its isomers by GC/MS to identify synthetic and semi-synthetic borneol products. (2018) Chirality 30(11), 1233-1239.
16. Ho TJ, Hung CC, Shih TL, Yiin LM,* Chen HP.* Investigation of borneols sold in Taiwan by chiral gas chromatography. (2018) Journal of Food and Drug Analysis 26(1), 348-352.

中文散文

1. 陸乃甄、賴尚志、何宗融、陳灝平.* 『乳香』的檢驗與活性分析-兼談『金創膏』在傷口照護的進展 (2022) 北台灣中醫醫學雜誌 14 (2): 17-32.
2. 盧昱竹、吳家如、洪崧壬、林榮興、陳中奎、謝明穎、蔡婉婷、何宗融*、陳灝平* 中藥『三黃散』對燙傷的療效研究 (2021) 中醫藥研究論叢 24 (1): 9-23.
3. 陸乃甄、何宗融、林明德、Preethi Krishnaraj、賴尚志、陳灝平.* 談坊間市售血竭的種類與生物活性分析 (2019) 北台灣中醫醫學雜誌，11 (1): 1-11.
4. 吳鐘霖、何宗融、吳炫璋、陳灝平.* 談中藥材『冰片』的分類、鏡像分析與歸經的感受 (2017) 北台灣中醫醫學雜誌，9 (1): 23-33.
5. 何宗融、陳灝平.* 談中藥『金創膏』於慢性不癒合傷口的治療及生物活性分析 (2016) 北台灣中醫醫學雜誌，8 (2): 13-20.

專利

1. 許鴻猷、林光慧、陳灝平。 一種檢測鮑氏不動桿菌之方法及其使用之試劑。中華民國發明專利，專利號碼: 1673364。
2. 陳灝平。食樹脂假單胞菌、冰片脫氫酶、含其之混合物、及其應用。中華民國發明專利，專利號碼: 108111234。
3. 胡安仁、洪崧仁、施增廉、陳灝平。殺菌劑及其用途。中華民國發明專利，專利號碼: 109131334。
4. 陳灝平。食樹脂假單胞菌、冰片脫氫酶、含其之混合物、及其應用。中華人民共和國發明專利，專利號碼: ZL 2019 1 0253002.4。