概 論
有時我們會以為自己有胃潰瘍而去看醫生,但其實潰瘍不是背後原因。也許你也曾有過似刀割般的上腹痛,但診斷性的檢查沒有顯示有潰瘍或其他消化性問題—所有的檢查都正常。如果你有上述的情形,那你可能患有 “非潰瘍性的消化不良”(nonulcer dyspepsia)。在英文中, “ dyspepsia”源自於希臘文字根 dys (困難) 和 pepsia (消化)。
非潰瘍性消化不良是一種常見,有時慢性的上消化道(包括食道,胃,和十二指腸的第一部份)失調,。它可以引起類似潰瘍的症狀,如上腹痛,不適,及時常伴隨的腹脹,打嗝,和噁心。
內視鏡射頻消融術

106年1月門診衛教活動,歡迎各位踴躍參與~~~~
時間 : 每週三,13:30~13:50
地點 : 泌尿部門診

醫師代碼:2310
專 長
‧上下消化道鏡檢查
‧逆行性膽胰造影術
‧消化道早期癌黏膜下剝離術
消化道內視鏡超音波
肛門直腸測壓術
脂肪肝及減重治療
腹部超音波
前言
你或許也曾經體驗過胸口灼熱的狀況而且伴隨著食物回流到嘴裡的感覺。這是胃食道逆流造成的,是一種胃酸(偶爾還會有膽汁)回流到食道裡的狀況。如果有證據顯示食道有受刺激而發炎,你就是得到了胃食道逆流症。
正常來說,下食道括約肌阻止了絕大部分胃酸的逆流。這條帶狀,位於食道底部的肌肉除了吞嚥的時候,平常是不開啟的。如果這肌肉有不正常的開啟或是減弱,胃酸就得以逆流及胸口不適或灼熱。
內視鏡手術


醫師代碼:23010
專長
.腹部超音波
.胃食道逆流
1. 如果你有以下的症狀
灼熱感/胃痛
腹瀉
嘔吐
便秘
腹痛
一個月至少一次,但一個禮拜不超過兩次 【加25分】
一個禮拜超過兩次 【加50分】
內視鏡超音波


醫師代碼:23030
專 長
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胃食道逆流症之進階診斷與治療
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食道蠕動障礙疾病診斷與治療
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腦腸軸溝通障礙疾病診斷與治療(如大腸激躁症、功能性消化不良症與功能性食道疾病)
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消化性潰瘍與幽門螺旋桿菌治療
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慢性B、C型肝炎、肝硬化、肝癌,脂肪肝相關疾病診斷與治療
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一般腸胃肝膽胰疾病診斷與治療
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各類診斷及治療性胃鏡、大腸鏡、超音波及肝纖維掃描儀檢查
現 職
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花蓮慈濟醫院腸胃肝膽科主治醫師
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慈濟大學醫學系教授
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社團法人台灣胃腸神經與蠕動學會第四屆秘書長
學 歷
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高雄醫學大學醫學系學士
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慈濟大學醫學科學研究所博士
經 歷
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關山慈濟醫院腸胃肝膽科主治醫師
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慈濟大學醫學系副教授
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慈濟大學醫學系助理教授
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社團法人台灣胃腸神經與蠕動學會第三屆秘書長
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日本東京崎玉醫科大學內視鏡研修
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台北馬偕醫院住院醫師
簡易介紹
專科學會:
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台灣內科醫學會會員
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台灣消化系醫學會會員
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台灣內視鏡醫學會會員
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中華民國醫用超音波醫學會會員
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台灣胃腸神經與蠕動醫學會會員
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美國胃腸病學會會員
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美國胃腸神經與蠕動學會會員
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台灣肝癌醫學會會員
專科證書暨指導醫師
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內科專科醫師暨指導醫師
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消化系內科專科醫師暨指導醫師
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消化系內視鏡專科醫師暨指導醫師
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消化系超音波專科醫師
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肝癌專科醫師
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老人急重症專科醫師
著 作:
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Lei WY, Wang JH, Gyawali CP, Yi CH, Liu TT, Hung JS, Wong MW, Chen CL. Esophageal hypervigilance and mucosal integrity predict symptom outcomes in reflux patients with normal acid exposure. Neurogastroenterol Motil. 2025 Apr 28;e70062
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Lei WY, Hung JS, Wong MW, Liu TT, Yi CH, Gyawali CP, Chen CL. Effects of capsaicin on esophageal peristalsis in humans using high resolution manometry. Neurogastroenterol Motil. 2024 Dec;36:e14942.
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Yeh JH, Chen CL, Sifrim D, Fass R, Wang WL, Hsu CC, Lei WY*. Central neuromodulators for patients with functional esophageal disorders: A systematic review and meta-analysis. Dig Liver Dis. 2024 Oct; 56: 1675-1682. (Correspondence)
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Lei WY, Yi CH, Liu TT, Hung JS, Wong MW, Chen CL. Esophageal motor abnormalities in gastroesophageal reflux disorders.Tzu Chi Med J 2024; 36: 120-126
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Lei WY, Liu TT, Chang WC, Yi CH, Hung JS, Wong MW, Liang SW, Lin L, Chen CL. Effects of Codeine on Esophageal Peristalsis in Patients with Ineffective Esophageal Motility: Studies Using High-resolution Manometry. J Neurogastroenterol Motil 2024 Jan; 30:38-45
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Lei WY, Lee Jian-Yu, Chuang Shu-Ling, et al. Eradicating helicobacter pylori via 13C-urea breath screening to prevent gastric cancer in indigenous communities: a population-based study and development of a family index-case method. Gut. 2023 Nov; 72:2231-2240
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Lei WY, Chen CL. Evaluation of post-POEM GERD: underestimate or overestimate? Am J. Gastroenterol 2023 Feb; 118: 372-373.
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Lei WY, Liang SW, Omari T, Chang WC, Wong MW, Hung JS, Yi CH, Liu TT, Lin L, Gyawali CP, Chen CL.* Transient hiatal separation during straight leg raise can predict reflux burden in gastroesophageal reflux desease patients with ineffective esophageal motility. J Neurogastroenterol Motil 2022 Oct; 28: 589-598.
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Lei WY, Liang SW, Hung JS, Wong MW, Liu TT, Yi CH, Lin L, Orr WC, Chen CL. Effects of menthol on esophageal motility in humans: Studies using high-resolution manometry. Neurogastroenterol Motil 2022 May; 34:e14267.
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Sawada A, Lei WY, Zhang M, Lee C, Ustaoglu A, Chen CL, Sifrim D. Esophageal mucosal sensory nerves and potential mechanoreceptors in patients with ineffective esophageal motility. Neurogastroenterol Motil 2022 Feb; 34(2): e14205 (co-first authors)
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Lei WY, Omari T, Liu TT, Wong MW, Hung JS, Yi CH, Liang SW, Cock C, Chen CL. Esophageal bolus domain pressure and peristalsis associated with experimental induction of esophagogastric junction outflow obstruction. J Neurogastroenterol Motil 2022 Jan 30;28:62-68.
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Chen CL, Wong MW, Hung JS, Liang SW, Liu TT, Yi CH, Lin L, Orr WC, Lei WY.* Effects of codeine on esophageal peristalsis using high-resolution manometry. J Gastroentrol Hepaol. 2021 Dec; 36:3381-3386.(correspondence)
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Lei WY, Liu TT, Wang JH, Yi CH, Hung JS, Wong MW, Gyawali CP, Chen CL. Impact of ineffective esophageal motility on secondary peristalsis: Studies with high-resolution manometry. Neurogastroenterol Motil 2021 Apr;33(4): e14024
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Lei WY, Gyawali CP, Chang WC, Roman S, Wong MW, Yi CH, Liu TT, Hung JS, Liang SW, Chen CL. Application of a novel straight leg raise test during high-resolution manometry can predict esophageal contractile reserve in patients with gastroesophageal reflux disease. Neurogastroenterol Motil. 2021 Mar;33(3):e13996.
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Lei WY, Wang JH, Yi CH, Liu TT, Hung JS, Wong MW, Bair MJ, Vaezi MF, Orr WC, Chen CL. Association between use of proton pump inhibitors and colorectal cancer: A nationwide population-based study. Clin Res Hepatol Gastroenterol 2021 Jan; 45:101397
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Lei WY, Vaezi MF, Naik RD, Chen CL. Mucosal impedance testing: A new diagnostic testing in gastroesophageal reflux disease. J Formos Med Assoc. 2020 Nov;119: 1575-1580.
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Lei WY, Chang WC, Wen SH, Yi CH, Liu TT, Hung JS, Wong MW, Chen CL. Predicting factors of recurrence in patients with gastroesophageal reflux disease: a prospective follow-up analysis. Therap Adv Gastroenterol. 2019 Jul 24;12:1756284819864549.
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Lei WY, Hung JS, Yi CH, Liu TT, Wong MW, Chen CL. Effects of esophageal acid infusion vs Mosapride on distension-induced secondary peristalsis in humans. Kaohsiung J. of Med. Sci. 2019 May;35(5):310-314
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Lei WY, Chang WC, Wen SH, Wong MW, Hung JS, Yi CH, Liu TT, Hsu CS, Orr WC, Vaezi MF, Hsieh TC, Chen CL. Impact of concomitant dyspepsia and irritable bowel syndrome on symptom burden in patients with gastroesophageal reflux disease. J Formos Med Assoc. 2019 Apr; 118(4):797-806.
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Lei WY, Chang WC, Wong MW, Hung JS, Wen SH, Yi CH, Liu TT, Chen JH, Hsu CS, Hsieh TC, Chen CL. Sleep Disturbance and Its Association with Gastrointestinal Symptoms/Diseases and Psychological Comorbidity. Digestion. 2019;99(3):205-212.
Services to medical journals
Reviewer for
Journal of Gastroenterology and Hepatology
Neurogastroenterology & Motility
Helicobacter
European journal of medical research
The Kaohsiung Journal of Medical Sciences
PLOS ONE
Advances in Digestive Medicine
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Tzu Chi Medical Journal

醫師代碼:23036
專長
.腹部超音波
.內視鏡超音波
「睡前上廁所」是許多人預防半夜一直爬起來尿尿的方式,然而許多民眾認為睡覺期間常因尿意醒來,一個晚上要跑廁所好幾次並不礙事。花蓮慈濟醫院泌尿部,從八月開始,每周三下午一點三十分,在泌尿門診區舉辦衛教講座
近年來,青少年濫用藥物嚴重,特別是K他命吸食成癮,還可能造成泌尿功能嚴重受損,導致必須包尿布過生活,須接受膀胱重建手術才可能獲得改善。花蓮慈濟醫院泌尿部主任郭漢崇指出,暑假結束後,K他命的問題也隨著開學浮現,他建議吸食上癮者要及早就醫治療,讓毒品對身體的危害降到最低。

醫師代碼:23057
專長
.一般內科
.一般腸胃肝膽疾病
.上下消化道內視鏡及超音波檢查
.B、C型肝炎、慢性肝炎及肝硬化治療等肝臟疾病
.急、慢性膽胰相關疾病
.胃食道逆流(GERD)、消化性潰瘍等消化疾病
.腹部超音波
.胃鏡、大腸鏡及相關內視鏡治療術
.氣囊式小腸纖維內視鏡檢查
.小腸膠囊內視鏡術
.膽胰治療性內視鏡攝影及相關治療術( ERCP )
.內視鏡經皮胃造廔術 ( PEG )
現 職
.佛教慈濟醫療財團法人花蓮慈濟醫院 腸胃內科 主治醫師
.慈濟大學醫學系 部定助理教授
學 歷
.慈濟大學 醫學士 (M.D.)
經 歷
.佛教慈濟醫療財團法人花蓮慈濟醫院 內科部住院醫師
.佛教慈濟醫療財團法人花蓮慈濟醫院 內科部總醫師
.佛教慈濟醫療財團法人花蓮慈濟醫院 腸胃內科 總醫師
.佛教慈濟醫療財團法人花蓮慈濟醫院 腸胃內科 臨床研究醫師
.日本東京崎玉醫科大學內視鏡研修
專科證書
.內科專科醫師證書
.消化系內科專科醫師證書
.消化系內視鏡專科醫師證書
.膽胰治療性內視鏡認證醫師證書
專科證書
.台灣內科醫學會
.台灣消化系醫學會
.台灣消化系內視鏡醫學會
.台灣發炎性腸道疾病學會
.台灣胃腸神經與蠕動學會
.台灣小腸醫學會
.台灣肝癌醫醫會
行醫三十多年,花蓮慈濟院泌尿科主任郭漢崇醫師不僅以泌尿醫學專業醫治了無數病患,更以一顆熱情澎湃的心,帶領團隊真誠為脊髓損傷病友付出關懷。將近四分之一世紀照護脊髓損傷病友排尿障礙的服務經驗與成果,經財團法人國家生技醫療產業策進會評審團三階段審查,獲得二○一二年SNQ「國家品質標章」的肯定。

楊先生,54歲男性,因血尿意外檢查出早期但具高惡性度的前列腺癌。醫療上,建議處置是接受「根除性前列腺切除手術」,這是泌尿科一項較高難度的手術...

醫師代碼:23073
專 長
.診斷及治療性內視鏡超音波(EUS):胰臟、膽道及消化道黏膜下腫瘤診治
.巴瑞特氏食道症(Barrett's esophagus)內視鏡射頻消融術(RFA)治療
.內視鏡抗逆流黏膜燒灼術(ARMA)治療
.肝癌射頻燒灼術(RFA)治療
.胃食道逆流症96小時無線膠囊酸鹼檢測
.脂肪肝、B、C型肝炎、慢性肝炎及肝硬化治療
.胃食道逆流、咽喉逆流症、胃、十二指腸潰瘍、脹氣消化不良
.腸躁症(IBS)、發炎性腸道疾病(IBD)
.胃鏡及大腸鏡、內視鏡息肉及腫瘤切除術、腹部超音波
現 職
.花蓮慈濟醫院肝膽腸胃科 主治醫師
.慈濟大學醫學院 副教授
學 歷
.台北醫學大學 醫學士
.慈濟大學藥理暨毒理學研究所 博士
經 歷
.美國西北大學(Northwestern Medicine)訪問學者
.日本東京大學醫學部附屬病院 內視鏡超音波(EUS)研修
.日本順天堂大學 肝癌射頻燒灼術(RFA)訓練
.台北馬偕醫院肝膽腸胃科 主治醫師
.台東馬偕醫院肝膽腸胃科 主治醫師
.台北馬偕醫院肝膽腸胃科 研究醫師
.台北馬偕醫院內科部 住院醫師及總醫師
專科證書
.內科專科醫師證書
.消化系內科專科醫師證書
.消化系內視鏡專科醫師證書
.醫教會一般醫學師資
專科學會
.台灣內科醫學會
.台灣消化系醫學會
.台灣消化系內視鏡醫學會
.台灣發炎性腸道疾病學會
.台灣胃腸神經與蠕動學會
.台灣微菌聯盟
.美國胃腸科醫學會
著 作
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Practical Application of the COuGH RefluX Score for Patients with Laryngopharyngeal Symptoms: Real-World Assessment in Predicting GERD and PPI Response. Wong MW, Hsiao SH, Wang JH, Hung JS, Liu TT, Lei WY, Yi CH, Chen PR, Gyawali CP, Chen CL.Am J Gastroenterol. 2024 Nov 26. doi: 10.14309/ajg.0000000000003240. Epub ahead of print.
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Impact of Esophageal Motility on Microbiome Alterations in Symptomatic Gastroesophageal Reflux Disease Patients With Negative Endoscopy: Exploring the Role of Ineffective Esophageal Motility and Contraction Reserve. Wong MW, Lo IH, Wu WK, Liu PY, Yang YT, Chen CY, Wu MS, Wong SH, Lei WY, Yi CH, Liu TT, Hung JS, Liang SW, Gyawali CP, Chen CL.Neurogastroenterol Motil. 2024 Jul 30;30(3):332-342.
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Mucosal integrity and acid sensitivity predict proton pump inhibitor response in patients with heartburn and normal acid exposure. Wong MW, Yi CH, Liu TT, Lei WY, Hung JS, Wang JH, Gyawali CP, Chen CL. Dig Liver Dis. 2025 Apr;57(4):842-848.
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Esophageal hypervigilance and visceral anxiety contribute to symptom severity of laryngopharyngeal reflux. Wong MW, Hsiao SH, Wang JH, Yi CH, Liu TT, Lei WY, Hung JS, Liang SW, Lin L, Gyawali CP, Chen PR and Chen CL. American Journal of Gastroenterology. 2023 May 1;118(5):786-793.
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Artificial intelligence facilitates measuring reflux episodes and post reflux swallow-induced peristaltic wave index from impedance-pH studies in patients with reflux disease. Wong MW, Liu MX, Lei WY, Liu TT, Yi CH, Hung JS, Liang SW, Lin L, Tseng CW, Wang JH, Wu PA, Chen CL.Neurogastroenterol Motil. 2023 Mar;35(3):e14506.
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Esophageal secondary peristalsis following acid infusion and chemical clearance correlate with mucosal integrity and acid sensitivity in GERD patients. Wong MW, Hung JS, Lei WY, Liu TT, Yi CH, Liang SW, Gyawali CP, Wang JH, Chen CL. Therap Adv Gastroenterol. 2023 Jun 29;16:17562848231179329.
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Oesophageal hypervigilance and visceral anxiety relate to reflux symptom severity and psychological distress but not to acid reflux parameters.Wong MW, Liu TT, Yi CH, Lei WY, Hung JS, Cock C, Omari T, Gyawali CP, Liang SW, Lin L, Chen CL. Aliment Pharmacol Ther. 2021 Oct;54(7):923-930
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Analysis of contractile segment impedance during straight leg raise maneuver using high-resolution impedance manometry increases diagnostic yield in reflux disease. Wong MW, Liu TT, Yi CH, Lei WY, Hung JS, Omari T, Cock C, Liang SW, Gyawali CP, Chen CL. Neurogastroenterology & Motility. 2021;00:e14135.
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Effect of prucalopride on sildenafil-induced inhibition of esophageal peristalsis in healthy adults. Wong MW, Liu TT, Yi CH, Hung JS, Lei WY, Liang SW, Orr WC, Chen CL. J Gastroenterol Hepatol. 2021 Jun;36(6):1556-1561.
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Esophageal acid burden in reflux patients with normal endoscopy: Does esophageal peristalsis matter? Wong MW, Hung JS, Liu TT, Yi CH, Lei WY, Liang SW, Orr WC, Chen CL. J Formos Med Assoc. 2021 Jun 2;S0929-6646(21)00236-9.
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Effects of phosphodiesterase-5 inhibitor sildenafil on esophageal secondary peristalsis: studies with high-resolution manometry. Wong MW, Yi CH, Liu TT, Lei WY, Hung JS, Liu CZ, Chen CL. J Gastroenterol Hepatol. 2021 Feb;36(2):430-435.
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Influence of sildenafil on esophageal motor function in humans: studies using high-resolution manometry. Wong MW, Hung JS, Lei WY, Liu TT, Yi CH, Chen CL. Neurogastroenterol Motil. 2020 Apr 23;e13840.
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Esophageal acid sensitivity in patients with gastroesophageal reflux disease: does esophageal hypomotility matter? Wong MW, Hung JS, Lei WY, Liu TT, Yi CH, Chen CL. Neurogastroenterol Motil. 2019 Nov;31(11):e13700.
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Clinical and psychological characteristics in gastroesophageal reflux disease patients overlapping with laryngopharyngeal reflux symptoms. Wong MW, Bair MJ, Chang WC, Hsu CS, Hung JS, Liu TT, Yi CH, Lei WY, Vaezi MF, Gyawali CP, Chen CL.J Gastroenterol Hepatol. 2019 Oct;34(10):1720-1726.
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Gamma‐aminobutyric acid receptor type B agonist baclofen inhibits acid‐induced excitation of secondary peristalsis but not heartburn sensation. Wong MW, Hung JS, Liu TT, Yi CH, Lei WY, Chen CL. J Gastroenterol Hepatol. 2019 Feb;34(2):370-375.
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Assessment of esophageal function using provocative tests during high resolution manometry: a single-center experience. Wong MW, Lei WY, Hung JS, Liu TT, Yi CH, Chen CL. J Formos Med Assoc. 2019 Jan;118(1 Pt 2):244-248.
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Validated Clinical Score to Predict Gastroesophageal Reflux in Patients With Chronic Laryngeal Symptoms: COuGH RefluX. Amanda J Krause, Alexander M Kaizer, Dustin A Carlson, Walter W Chan, Chien-Lin Chen, C Prakash Gyawali, Andrew Jenkins, John E Pandolfino, Vinathi Polamraju, Ming-Wun Wong, Madeline Greytak, Rena Yadlapati. Clin Gastroenterol Hepatol. 2024 Jun;22(6):1200-1209.e1.
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Diagnostic Yield of Ambulatory Reflux Monitoring Systems for Evaluation of Chronic Laryngeal Symptoms. Amanda J Krause, Madeline Greytak, Alexander M Kaizer, Dustin A Carlson, Walter W Chan, Chien-Lin Chen, C Prakash Gyawali, Andrew Jenkins, John E Pandolfino, Vinathi Polamraju, Ming-Wun Wong, Rena Yadlapati. Am J Gastroenterol. 2024 Apr 1;119(4):627-634.
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The Lyon Score: A Novel Reflux Scoring System Based on the Lyon Consensus 2.0 That Associates With Treatment Outcome From Antireflux Therapy. Gyawali CP, Marchetti L, Rogers BD, Chan WW, Wong MW, Visaggi P, Rengarajan A, Carlson DA, Savarino E, de Bortoli N, Chen CL, Pandolfino JE.Am J Gastroenterol. 2025 May 1;120(5):1009-1018.
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Validation of Esophageal Global Symptom Severity as a Patient-Reported Outcome for Evaluation of Reflux Symptoms. Chan WW, Schroeder M, Richardson A, Shah N, Muftah M, Muftah S, Siboni S, Sozzi M, Wong MW, Chen CL, Gyawali CP; Milan Score Working Group.Am J Gastroenterol. 2025 Apr 23. doi: 10.14309/ajg.0000000000003499. Epub ahead of print.
專利
.Computer-Assisted Medical Analysis System and Method, Device, Computer Storage Medium and Computer Program Product For Interpreting Gastroesophageal Reflux Disease Using Artificial Intelligence.
發明人:翁銘彣、劉民翔、吳彬安、陳健麟
專利證書字號:發明第I817685號