醫師代碼：23010
專長
．腹部超音波
．胃食道逆流
．上消化道內視鏡
．下消化道內視鏡
．肝癌治療
．B型肝炎治療
．C型肝炎治療
現 職
．肝膽腸胃主治醫師
．慈濟大學部定副教授
學 歷
．國立成功大學學士醫學系
經 歷
．馬偕紀念醫院內科住院醫師
．花蓮慈濟醫院內科住院醫師
．花蓮慈濟醫院肝膽腸胃科研究員
．花蓮慈濟醫院內科總醫師
．國立成功大學肝膽腸胃科訓練
．花蓮慈濟醫院玉里分院內科主治醫師
．花蓮慈濟醫院肝膽腸胃科主治醫師
．消化系功能檢查室主任
簡易介紹
專科證書：
．內科專科醫師證書
．消化系內科專科醫師證書
．消化系內視鏡專科醫師證書
．消化系超音波專科醫師證書
專科學會：
．台灣內科學會
．台灣消化系醫學會
．台灣內視鏡醫學會
著 作：
1. Chih-Hsun Yi, Wei-Yi Lei, Jui-Sheng Hung, Tso-Tsai Liu, William C. Orr, Pace Fabio, Chien-Lin Chen*. Differences in the Control of Secondary Peristalsis in the Human Esophagus: Influence of the 5-HT4 Receptor versus the TRPV1 Receptor. PLOS ONE 2016 Jul 20;11(7):e0159452. (SCI)
2. Chih-Hsun Yi, Tso-Tsai Liu, Wei-Yi Lei, Jui-Sheng Hung, Chien-Lin Chen*. Influence of rectal decompression on abdominal symptoms and anorectal physiology following colonoscopy in health adults. Gastroenterology Research and Practice Volume 2016, Article ID 4101248, 5 pages. (SCI)
3. Chih-Hsun Yi, Wei-Yi Lei, Jui-Sheng Hung, Tso-Tsai Liu and Chien-Lin Chen*. Effects of prucalopride on esophageal secondary peristalsis in humans. Clin Transl Gastroenterol. 2016 Nov; 7(11): e202. (SCI)
4. Chih-Hsun Yi, Wei-Yi Lei, Jui-Sheng Hung, Tso-Tsai Liu, Chien-Lin Chen* and Pace Fabio. Influence of capsaicin infusion on secondary peristalsis in patients with gastroesophageal reflux disease. World J Gastroenterol. 2016 Dec 7; 22(45): 10045–10052. (SCI)
5. Chih-Hsun Yi, Wei-Yi Lei, Jui-Sheng Hung, Tso-Tsai Liu, William C. Orr, Chien-Lin Chen*. Relevance of Sleep Disturbance to the Integrity and Characteristics of Secondary Peristalsis in Patients with Gastroesophageal Reflux Disease. Scand J Gastroenterol. 2017 Feb;52(2):136-142. (SCI)
6. Lei WY, Hung JS, Liu TT, Yi CH, Chen CL*. Influence of GABA-B Agonist Baclofen on Capsaicin-Induced Excitation of Secondary Peristalsis in Humans. Clin Transl Gastroenterol. 2017 Oct 5;8(10):e120. (SCI)
7. Lei WY, Hung JS, Liu TT, Yi CH, Chen CL*. Altered oesophageal mechanosensitivity of secondary peristalsis as a pathophysiological marker in patients with globus sensation. Clinical Otolaryngology 2018 Feb;43(1):306-311. (SCI)
8. Chien-Lin Chen, Wei-Chuan Chang, Chih‐Hsun Yi, Jui-Sheng Hung, Tso-Tsai Liu, Wei-Yi Lei, Ching-Sheng Hsu. Association of coffee consumption and liver fibrosis progression in patients with HBeAg‐negative chronic hepatitis B: A 5-year population-based cohort study. J Formos Med Assoc. 2019 Feb;118(2):628-635. (SCI)
9. Ming-Wun Wong, Jui-Sheng Hung, Tso-Tsai Liu, Chih‐Hsun Yi, Wei-Yi Lei and Chien-Lin Chen*. GABA-B agonist baclofen inhibits acid-induced excitation of secondary peristalsis but not heartburn sensation. J Gastroenterol Hepatol. 2019 Feb;34(2):370-375. (SCI)
10. Wei-Yi Lei, Jui-Sheng Hung, Chih‐Hsun Yi, Tso-Tsai Liu, Ming-Wun Wong, Chien-Lin Chen*. Effects of Esophageal Acid Infusion versus Mosapride on Distension-Induced Secondary Peristalsis in Humans. Kaohsiung J Med Sci. 2019 May;35(5):310-314. (SCI)
11. Lei WY, Chang WC, Wen SH, Yi CH, Liu TT, Hung JS, Wong MW, Chen CL*. Predicting factors of recurrence in patients with gastroesophageal reflux disease: a prospective follow-up analysis. Therap Adv Gastroenterol. 2019 Jul 24;12:1756284819864549. (SCI)
12. Wong MW, Hung JS, Lei WY, Yi CH, Liu TT, Chen CL*. Influence of sildenafil on esophageal motor function in humans: Studies using high-resolution manometry. Neurogastroenterol Motil. 2020 Jul;32(7):e13840. (SCI)
13. Wong MW, Yi CH, Liu TT, Lei WY, Hung JS, Liu CZ, Chen CL*. Effects of phosphodiesterase-5 inhibitor sildenafil on esophageal secondary peristalsis: studies with high-resolution manometry. J Gastroenterol Hepatol. 2021 Feb;36(2):430-435. (SCI)
14. Wong MW, Liu TT, Yi CH, Lei WY, Hung JS, Cock C, Omari T, Gyawali CP, Liang SW, Lin L, Chen CL*. Oesophageal hypervigilance and visceral anxiety relate to reflux symptom severity and psychological distress but not to acid reflux parameters. Aliment Pharmacol Ther. 2021 Oct;54(7):923-930. (SCI)
15. Wong MW, Liu TT, Yi CH, Lei WY, Hung JS, Omari T, Cock C, Liang SW, Gyawali CP, Chen CL*. Analysis of contractile segment impedance during straight leg raise maneuver using high-resolution impedance manometry increases diagnostic yield in reflux disease. Neurogastroenterol Motil. 2022 Jan;34(1):e14135. (SCI)
16. Wong MW, Hung JS, Liu TT, Yi CH, Lei WY, Liang SW, Orr WC, Chen CL*. Esophageal acid burden in reflux patients with normal endoscopy: Does esophageal peristalsis matter? J Formos Med Assoc. 2022 Jan;121(1 Pt 2):388-394. (SCI)
17. Wong MW, Liu TT, Yi CH, Lei WY, Hung JS, Omari T, Cock C, Liang SW, Gyawali CP, Chen CL*. Analysis of contractile segment impedance during straight leg raise maneuver using high-resolution impedance manometry increases diagnostic yield in reflux disease. Neurogastroenterol Motil. 2022 Jan;34(1):e14135. (SCI)
18. Lei WY, Liang SW, Hung JS, Wong MW, Liu TT, Yi CH, Lin L, Orr WC, Chen CL*. Effects of menthol on esophageal motility in humans: Studies using high-resolution manometry. Neurogastroenterol Motil. 2022 May;34(5):e14267. (SCI)
19. Yi CH, Bair MJ, Wang JH, Wong MW, Liu TT, Lei WY, Liang SW, Lin L, Hung JS, Huang JF, Hsu YC, Chen CL*. Improvement of patient-reported outcomes in patients achieving sustained virologic response with direct-acting antivirals for hepatitis C virus infection. J Microbiol Immunol Infect. 2022 Aug;55(4):643-650. (SCI)
20. Hung JS, Liang SW, Omari T, Wong MW, Lei WY, Yi CH, Liu TT, Lin L, Chen CL*. Effects of the GABA(B) agonist baclofen on volitional swallowing in normal subjects. Kaohsiung J Med Sci. 2023 Jan;39(1):80-86. (SCI)
21. Wong MW, Liu MX, Lei WY, Liu TT, Yi CH, Hung JS, Liang SW, Lin L, Tseng CW, Wang JH, Wu PA, Chen CL*. Artificial intelligence facilitates measuring reflux episodes and post reflux swallow-induced peristaltic wave index from impedance-pH studies in patients with reflux disease. Neurogastroenterol Motil. 2023 Mar;35(3):e14506. (SCI)
22. Wong MW, Hsiao SH, Wang JH, Yi CH, Liu TT, Lei WY, Hung JS, Liang SW, Lin L, Gyawali CP, Chen PR and Chen CL*. Esophageal hypervigilance and visceral anxiety contribute to symptom severity of laryngopharyngeal reflux. American Journal of Gastroenterology 2023 May 1;118(5):786-793. (SCI)
23. Wong MW, Hung JS, Lei WY, Liu TT, Yi CH, Liang SW, Gyawali CP, Wang JH, Chen CL*. Esophageal secondary peristalsis following acid infusion and chemical clearance correlate with mucosal integrity and acid sensitivity in GERD patients. Therap Adv Gastroenterol. 2023 Jun 29;16:17562848231179329. (SCI)
24. Lei WY, Liu TT, Chang WC, Yi CH, Hung JS, Wong MW, Liang SW, Lin L, Chen CL*. Effects of Codeine on Esophageal Peristalsis in Patients With Ineffective Esophageal Motility: Studies Using High-resolution Manometry. J Neurogastroenterol Motil. 2024 Jan 30;30(1):38-45. (SCI)
25. Lei WY, Yi CH, Liu TT, Hung JS, Wong MW, Chen CL. Esophageal motor abnormalities in gastroesophageal reflux disorders. Tzu Chi Med J. 2024 Mar 26;36(2):120-126.
