Li-Yi Sun, Director

Phone : 03-8561825 #15931

E-mail : Email住址會使用灌水程式保護機制。你需要啟動Javascript才能觀看它 ; Email住址會使用灌水程式保護機制。你需要啟動Javascript才能觀看它

Special Expertise

• Somatic preparation GTP process development                                                                            
• Stem Cell Biology
• Animal Cell Bioreactor
• Adout stem cell in vitro mass production process development
• Establishment of cell model for drug testing
• ISO17025 Laboratory Quality System

Current position

• Director, Gene and Stem Cells Manufacturing Center, Hualien Tzu Chi Hospital

Education

• Doctor, Department of Biological Science and Technology, National Chiao Tung University
• Master, Institute of Biotechnology , National Dong Hwa University
• Department of Life Science, National Dong Hwa University

Experience

• Assistant Research Fellow, Department of Medical Research, Gene and Stem Cells Manufacturing Center, Hualien Tzu Chi Hospital
• Postdoctoral Research Fellow, Department of Medical Research, Gene and Stem Cells Manufacturing Center, Hualien Tzu Chi Hospital
• Postdoctoral Research Fellow, Institute of Polymer Science and Engineering, National Taiwan University
• Director of R&D and Project manager, GUANG Li BIOMEDICINE
• Assistant Research Fellow, Department of  R&D TENSALL BIO-TECH

Related Certificate

    GTP Related Certificate

• TAF-TH99004-C-21
• TAF-QM99007-C-17
• TAF-MM99004-C-36
• (98)GTP訓98-GTP3-008字第31號
• (99)GTP培訓證字990427B-32號
• (99)GTP培訓證字第990510-036號
• (99)GTP培訓證字990727A-34號
• GTP100090025
• GTP100100027
• GTP100110029
• GTP101050088

 Major achievements in the industry

• Establish GUANG Li BIOMEDICINE GTP Lab
• Establish SVF storage specification
• Establish Adipose stem cells serum free culture techniqe
• Developed mesenchymal stem cell rapid proliferation adjuvant-MitoBurst and technology transfer to Taiwan Advance Bio-Pharmaceutical Inc. (TABP)

Publication

1. Sun LY, Hsieh DK, Yu TC, Chiu HT, Lu SF, Luo GH, Kuo TK, Lee OK, Chiou TW. Effect of pulsed electromagnetic field on the proliferation and differentiation potential of human bone marrow mesenchymal stem cells. Bioelectromagnetics. 2009 May; 30(4): 251-60. (IF: 2.759. BIOLOGY: 18/76)
    
2. Sun LY, Hsieh DK, Yu TC, Chiu HT, Lu SF, Luo GH, Kuo TK, Lee OK, Chiou TW. Effect of pulsed electromagnetic field on the proliferation and differentiation potential of human bone marrow mesenchymal stem cells. Bioelectromagnetics. 2009 May; 30(4): 251-60. (IF: 2.759. BIOLOGY: 18/76)
    
3. Sun LY, Hsieh DK, Syu WS, Li YS, Chiu HT, Chiou TW. Cell proliferation of human bone marrow mesenchymal stem cells on biodegradable microcarriers enhances in vitro differentiation potential. Cell Proliferation. 2010 Oct; 43(5): 445-56. (IF: 2.917. CELL BIOLOGY: 90/162)
    
4. Sun LY, LinSZ, LiYS, HarnHJ, Chiou TW. Functional cells cultured on microcarriers for use in regenerative medicine research. Cell Transplantation. 2010; 20(1):49-62. (Review) (IF: 5.126. TRANSPLANTATION: 2/24)
    
5. Chang YJ, Liu JW, Lin PC, Sun LY, Luo GH, Chen TM, Lee RP, Lin SZ, Harn HJ, Chiou TW. Mesenchymal stem cells facilitate recovery from chemically induced liver damage and decrease liver fibrosis. Life Sci. 2009 Sep; 85(13-14): 517-25. (IF: 2.583. MEDICINE, RESEARCH & EXPERIMENTAL: 33/82)
    
6. Lin SZ, Chang YJ, Liu JW, Chang LF, Sun LY, Li YS, Luo GH, Liao CH, Chen PH, Chen TM, LeeRP, Yang KL, HarnHJ, Chiou TW. Transplantation of human Wharton’s jelly-derived stem cells alleviates chemically induced liver fibrosis in rats. Cell Transplantation. 2010; 19(11): 1451-63. (IF: 5.126. TRANSPLANTATION: 2/24)
    
7. Lin PC, Lin SZ, Chen YL, Chang JS, Ho LI, Liu PY, Chang LF, Harn YC, Chen SP, Sun LY, Huang PC, Chein JT, Tsai CH, Chou CW, Harn HJ, Chiou TW. Butylidenephthalide suppresses human telomerase reverse transcriptase (TERT) in human glioblastomas. Annals of Surgical Oncology. 2010. (IF: 4.13. SURGERY: 6/166)
    
8. Li-Yi Sun, Chen-Yoong Pang, Dian-Kun Li, Chia-Hsin Liao1, Wei-Chao Huang, Chao-Chuan Wu, Yi-Yo Chou, Wei Wu Li, Shin-Yuan Chen, Hwan-Wun Liu, Yao-Jen Chang, Ching-Feng Cheng. Antioxidants cause rapid expansion of human adipose-derived mesenchymal stem cells via CDK and CDK inhibitor regulation. Journal of Biomedical Science. 2013. (IF: 2.458. SURGERY: 57/121)
    
9. Li-Yi Sun, Dian-Kun Li, Pao-Jen Chen, Yu-Yu Joyce Ho, Jon-Son Kuo, Ching-Feng Cheng, Kuei-Fang Lee, Yao-Jen Chang, Cheng-Yoong Pang. Expansion of semi-automatic processed human adipose-derived stem cells in medium supplemented with autologous serum and antioxidants. Journal of Stem Cell Research & Therapy. 2014(IF: 5.86)