醫師代碼：23005
專 長
‧一般肝膽腸胃內科
‧胃食道逆流症
‧功能性腸胃疾病
‧特殊檢查: 食道功能儀及24小時食道酸鹼測定
現 職
‧花蓮慈院肝膽腸胃內科主任
‧花蓮慈院肝膽腸胃創新研究中心副主任
‧花蓮慈院肝膽腸胃內科主治醫師
‧花蓮慈濟大學內科部定教授
‧美國腸胃科學院院士（FACG)
‧社團法人台灣胃腸神經與蠕動學會 第三屆 理事長
‧台灣消化系內視鏡醫學會 第十一屆 理事
‧台灣內科醫學會 第十三屆副秘書長
學 歷
‧陽明大學醫學系學士
‧澳洲新南威爾斯大學醫學博士
經 歷
‧台北市立仁愛醫院住院醫師、住院總醫師
‧三重醫院主治醫師
‧美國奧克拉荷馬州Lynn腸胃蠕動研究中心研究員/專任醫師
‧澳洲新南威爾斯聖喬治醫院胃腸科研究員（Researchfellow,DepartmentofGastroenterology,TheStGeorgeHospital,Kogarah,NSW,Australia）
簡易介紹
專科證書：
．內科專科醫師證書
．消化系內視鏡專科醫師證書
．消化系內科專科醫師證書
專科學會：
‧台灣內科醫學會
‧台灣消化系醫學會
‧台灣消化系內視鏡學會
‧台灣醫用超音波醫學會
‧美國胃腸科醫學會
‧美國腸胃科學院
‧美國生理科醫學會
‧美國胃腸動力學會
著 作：
Journal
1.The role of age and salivation in acid clearance in symptomatic patients with gastro-oesophageal reflux disease. Aliment Pharmacol Ther 2001;15:1385-8. Orr WC, Chen CL and Sloan S. (SCI)
2.Efficacy of a motilin receptor agonist (ABT-229) for the treatment of gastro-oesophageal reflux disease. Aliment Pharmacol Ther 2002;16:749-57. Chen CL, Orr WC, Verlinden MH, et al. (SCI)
3.Aging and neural control of the GI tract: IV. Clinical and physiological aspects of gastrointestinal motility and aging. Am J Physiol Gastrointest Liver Physiol 2002;283:G1226-31. Orr WC and Chen CL. (SCI)
4.Autonomic responses to heartburn induced by esophageal acid infusion. J Gastroenterol Hepatol 2004;19:922-6. Chen CL and Orr WC. (SCI)
5.Gastric dysrhythmias and transient sleep impairment in healthy subjects. Dig Dis Sci 2004;49:176-9. Chen CL and Lin HH. (SCI)
6.Transfer function analysis of heart rate variability in response to water intake: correlation with gastric myoelectrical activity. J Appl Physiol 2004;96:2226-30. Chen CL, Lin HH, Orr WC, et al. (SCI)
7.Electrogastrography differentiates reflux disease with or without dyspeptic symptoms. Dig Dis Sci 2004;49:715-9. Chen CL, Lin HH, Huang LC, et al. (SCI)
8.Gastric myoelectrical activity in GERD overlapping with dysmotility dyspepsia. Gastroenterol J Taiwan 2004;21:1-10. Chen CL, Lin HH, Huang LC, Huang SC, Hu CT and Liu TT.
9.Colonoscopic diagnosis of whipworm infection. J Gastroenterol Hepatol 2005;20:965-7. Lin AT, Lin HH and Chen CL. (SCI)
10.Utility of electrogastrography in differentiating Parkinson's disease with or without gastrointestinal symptoms: a prospective controlled study. Digestion 2005;71:187-91. Chen CL, Lin HH, Chen SY, et al. (SCI)
11.Dyspeptic symptoms and water load test in patients with functional dyspepsia and reflux disease. Scand J Gastroenterol 2005;40:28-32. Chen CL, Lin HH, Chen MC, et al. (SCI)
12.Esophageal acid exposure in healthy adults in Taiwan: experience with pH step-up method by dual-channel pH-metry. Kaohsiung J Med Sci 2005;21:299-303. Yi CH, Chen CL, Lin HH, et al.
13.Sleep and the gastrointestinal tract. Neurol Clin 2005;23:1007-24. Orr WC and Chen CL. (SCI)
14.A comparison of esophageal motility in patients with solid dysphagia and mixed dysphagia. Dysphagia 2005;20:261-5. Chen CL and Orr WC. (SCI)
15.Clinical challenges and images in GI. Mycotic aneurysm of the superior mesenteric artery. Gastroenterology 2006;131:13,337. Chen CL, Chou ASB and Chiu CH. (SCI)
16.The effect of laproscopic nissen fundoplication on symptoms and gastric myoelectric activity in GERD. J Clin Gastroenterol 2006;40:301-5. Chen CL, Reif ME and Orr WC. (SCI)
17.Cardiac autonomic regulation differentiates reflux disease with and without erosive esophagitis. Scand J Gastroenterol 2006;41:1001-6. Chen CL, Orr WC, Yang CCH and Kuo TBJ. (SCI)
18.Cardiac Autonomic Dysregulation in Patients with Acute Hepatitis. The American Journal of the Medical Sciences 2006;332:164-67. Chen KY, Chen CL, Yang CCH and Kuo TBJ. (SCI)
19.Clinical utility of electrogastrography and the water load test in patients with upper gastrointestinal symptoms. Journal of Smooth Muscle Research 2006;42:149-57. Chen CL, Hu CT, Lin HH and Yi CH.
20.Utility of ambulatory pH monitoring and videofluoroscopy for the evaluation of patients with globus pharyngeus. Dysphagia 2007;22:16-19. Chen CL, Tsai CC, Chou ASB and Chiou JH. (SCI)
21.Assessment of esophageal motor function using combined multichannel intraluminal impedance and manometry in healthy volunteers: a single-center study in Taiwan. J Gastroenterol Hepatol 2007;22:1039-43. Chen CL and Yi CH. (SCI)
22.Sleep Dysfunction in Patients with GERD: Erosive versus Non-erosive Reflux Disease. The American Journal of the Medical Sciences 2007;334(3):168-70. Yi CH, Hu CT and Chen CL. (SCI)
23.Transfer Function Analysis of Heart Rate Variability Correlated with Gastric Myoelectrical Activity Using a Liquid Nutritional Meal Compared to Water: Are They Different? The Chinese Journal of Physiology 2007;50(6):271-6. Chen CL, Yang CCH and Kuo TBJ. (SCI)
24.Sleep symptoms and gastro-esophageal reflux. J Clin Gastroenterol 2008;42:13-17. Chen CL, Jennifer J.T. Robert and William C.Orr. (SCI)
25.Effect of Acid Suppression on Gastric Myoelectrical Activity in GERD. Hepato-Gastroenterology 2008; 55:1353-1355.Chen CL, Yi CH, Yang CCH and Kuo TBJ. (SCI)
26.Gender difference in anorectal function in healthy young Taiwanese. Gastroenterol J Taiwan 2008;25(2):171-175. Liu TT, Chen CL, Yi CH, Tung PC, and Chen CH.
27.Utility of esophageal impedance in identifying dysmotility in patients with erosive esophagitis. Diseases of the Esophagus 2008;21(6):541-543. Chen CL and Yi CH. (SCI)
28.Clinical correlates of dysphagia to oesophageal dysmotility: studies using combined manometry and impedance. Neurogastroenterol Motil 2008; 20:611-617. Chen CL and Yi CH. (SCI)
29.Anorectal Manometry in Patients with Chronic Constipation: A Single-center Experience. Hepato-Gastroenterology 2008;55(82-83):426-9. Liu, TT, Chen CL, and Yi CH. (SCI)
30.The Effect of Acid Suppression on Sleep and Cardiac Autonomic Regulation in GERD. Hepato-Gastroenterology 2008; 55:1655-1658. Yi CH, Chen CL, Kuo TBJ and Yang CCH. (SCI)
31.Differences in esophageal bolus transit between patients with and without erosive reflux disease. Digestive and Liver Disease 2008;40(5):348-54. Chen CL, Yi CH, and Cook IJ. (SCI)
32.Identification of impaired oesophageal bolus transit and clearance by secondary peristalsis in patients with non-obstructive dysphagia. Neurogastroenterol Motil 2008;20:980-988. Chen CL, Szczesniak MM, and Cook IJ. (SCI)
33.Oesophageal bolus transit and clearance by secondary peristalsis in normal subjects. Eur J Gatroen Hepat 2008. (accepted) Chen CL, Szczesniak MM, and Cook IJ. (SCI)
34.Proximal versus distal esophageal motility as assessed by combined impedance and manometry. Digestive and Liver disease 2008 Aug 28. [Epub ahead of print] Chen CL and Cook IJ (SCI).
Conference abstracts
Domestic meeting
1.Gastric myoelectrical activity in gastroesophageal reflux disease overlaping with functional dyspepsia. Hung LC, Chen CL, Lin HH, et al. Gastroenterol J Taiwan 2003;20(1):74.
2.Effects of water ingestion on gastric vagal activity in humans-using transfer function analysis of heart rate variability. Chen CL, Kuo TBJ, Lin HH, et al. Gastroenterol J Taiwan 2003;20(1):74.
3.The water load test: observations from patients with functional dysphagia and GERD. Chen CL, Chen MC, Lin HH, et al. Gastroenterol J Taiwan 2003;20(2).
4.Simultaneous two levels esophageal pH monitoring: observations from healthy controls and patients with erosive esophagitis. Chen CL, Chen MC, Lin HH, et al. Gastroenterol J Taiwan 2004;21(1):59.
5.Twenty four-hours dual-probe pH monitoring in healthy adults in Taiwan. Chen MC, Chen CL, Lin HH, et al. Gastroenterol J Taiwan 2004;21(1):61.
6.Combination of ambulatory pH monitoring and videofluoroscopy for the evaluation of patients with globus pharyngeus. Yi CH, Chen CL, Lin HH, et al. Gastroenterol J Taiwan 2005;20(1):82.
7.Effect of GERD therapy on sleep function, gastric motility, and autonomic function in patients with reflux disease: a pilot study. Chen CL, Kuo TBJ, Lin HH, et al. Gastroenterol J Taiwan 2005;22(1):83.
8.The effect of laparoscopic nissen fundoplication on symptoms and gastric myoelectric activity in GERD. Hung LC, Chen CL, Orr WC, et al. Gastroenterol J Taiwan 2005;22(1):84.
9.Evidence for Visceral Hypersensitivity in Patients with Globus. Chen CL. Gastroenterol J Taiwan 2008;25(1):75.
10.Relationship Between Dysphagia and Esophageal Function in Patients with Non-obstructive Dysphagia. Chen CL, Yi CH, Liu TT, et al. Gastroenterol J Taiwan 2008;25(1):75.
11.Impact of Variable Type Colonoscopes on Colonoscopic Performance and Efficiency Population. Yi CH, Chen CL, Liu TT. Gastroenterol J Taiwan 2008;25(1):119.
12.The Impact of Intravenous Propofol on Anorectal Motility. Liu TT, Yi CH, Chen CL. Gastroenterol J Taiwan 2008;25(1):126.
13.Regional Differences in Esophageal Motility: Studies Using Combined Impedance and Manometry. Chen CL, Cook IJ. Gastroenterol J Taiwan 2008;25(3):75.
International meeting
1.The Effects of gastric distension on gastric myoelectrical activity in different symptomatic subgroups of patients with IBS. Chen CL, Harnish MJ, Spence A, Elesenbruch S, Orr WC. Biennial meeting, American Motility Society, 2000.
2.The effects of esophageal body peristalsis on esophageal acid clearance. Chen CL, Orr WC. Biennial meeting, American Motility Society, 2000.
3.The effects of mast cell stabilization on autonomic and pain responses to esophageal acidification. Chen CL, Orr WC. Gastroenterology 2001; 120: A629 [Abstract].
4.The effect of esophageal acidification on autonomic functioning in symptomatic GERD patients. Chen CL, Orr WC. Gastroenterology 2001; 120: A629 [Abstract].
5.Esophageal motor disorders in patients with non-obstructive dysphagia. Chen CL, Orr WC. Am J Gastroenterol 2001;96: S6 [Abstract].
6.Gastric myoelectrical activity before and after laparoscopic fundoplication for gastroesophgeal reflux. Chen CL, Orr WC. 12th Biennial meeting of American motility society. 2002.
7.The water load test in patients with functional gastrointestinal disorders. Chen CL, Lin HH, Chen MC. Am J Gastroenterol 2003;98: S41.
8.Gastric myoelectrical activity in reflux disease and after laparoscopic Nissen fundoplication. Chen CL, Reif ME, and Orr WC. International workshop on Electrogastrography, 2004.
9.Combination of ambulatory pH monitoring and videofluoroscopy for the evaluation of patients with globus pharyngeus. Chen CL, et al. Am J Gastroenterol 2004;99: S2.
10.Pattern of autonomic regulation differentiates reflux disease with and without erosive esophagitis. Chen CL, Kuo TBJ, and Orr WC. Gastroenterology 2005; 128: A518 [Abstract].
11.Effect of water and a liquid nutritional meal on gastric electric activity and heart rate variability in health human subjects. Chen CL, Kuo TBJ, and Yang CCH. Neurogastroenterol Motil 2005;17 Suppl 2: 82.
12.The Effect of Acid Suppression on Subjective Sleep, Gastric Myoelectrical functioning, and Cardiac Autonomic function in Patients with Erosive GERD. Chen CL. Gastroenterology 2006; April [Abstract].
13.Esophageal bolus transit and clearance by secondary peristalsis: studies using combined impedance-manometry. Chen CL, Cook IJ, Szczesniak M. Neurogastroenterol Motility 2007;19(s3):58.
14.Combined Multichannel Intraluminal Impedance and Manometry in Patients with and without Erosive Reflux Disease. Chen CL, Yi CH, Wang CC. 15th United European Gastroenterology Week "UEGW 2007" Paris, France.
15.Evidence for oesophageal mechanical hypersensitivity with aberrant viscerosomatic referral in patients with globus. Gastroenterology 2008;134(s1):560. Chen CL, Szczesniak M, Omari T, Cook IJ.
16.Identification of impaired bolus transit and clearance by secondary peristalsis in patients with non-obstructive dysphagia. Gastroenterology 2008;134(s1):716. Chen CL, Szczesniak M, Omari T, Cook IJ.
BOOK CHAPTER
1.Gastrointestinal monitoring in Principles and practice of sleep medicine. Fourth Edition. 2005. Orr WC, Chen CL.
2.Sleep and gastrointestinal functioning in Sleep and Psychosomatic Medicine, Informa Healthcare. First Edition. 2006. Chien-Lin Chen and William C Orr.
3.Quality of life and sleep disturbances in Gastroesophageal reflux disease in Sleep and Quality of Life in Clinical Medicine, Human Press. Fisrt Edition. 2008. Orr WC, Chen CL.
SERVICE TO MEDICAL JOURNALS
Reviewer for:
Neurogastroenterology and Motility
Scandinavian Journal of Gastroenterology
Dis Esophagus
